Enhancement of Solubility of Lamotrigine by Solid Dispersion and Development of Orally Disintegrating Tablets Using 3² Full Factorial Design

Table 5

Parameters of ODTs.

Parameters; formulations	Thickness; (mm)	Weight; (mg)	Hardness; (kg/cm^2)	DT; (s)	WT; (s)	Friability; (%)
ODT1	3.175 ± 0.014	151.8 ± 3.551	3.1 ± 0.152	32	40	0.69
ODT2	3.042 ± 0.026	150.7 ± 3.632	3.0 ± 0.096	27	35	0.66
ODT3	3.143 ± 0.034	149.2 ± 2.427	2.9 ± 0.126	21	31	0.62
ODT4	3.025 ± 0.004	147.8 ± 3.321	2.8 ± 0.134	20	30	0.59
ODT5	3.094 ± 0.037	151.1 ± 2.731	2.8 ± 0.157	17	25	0.56
ODT6	3.042 ± 0.029	146.5 ± 3.654	2.7 ± 0.095	15	24	0.55
ODT7	3.163 ± 0.034	149.8 ± 2.427	2.9 ± 0.126	14	23	0.54
ODT8	3.175 ± 0.024	150.8 ± 3.251	3.0 ± 0.153	13	22	0.52
ODT9	3.114 ± 0.047	149.1 ± 2.631	2.8 ± 0.167	11	21	0.55