Research Article
Enhancement of Solubility of Lamotrigine by Solid Dispersion and Development of Orally Disintegrating Tablets Using 32 Full Factorial Design
Table 6
This table shows goals and solution of optimized tablet as suggested by the software.
| | Constraints | | Name | Goal | Lower limit | Upper limit |
| | SSG | In range | −1 | 1 | | Crospovidone | In range | −1 | 1 | | DT (s) | Target = 15 | 11 | 32 | | WT (s) | In range | 21 | 40 | | Friability (%) | Minimize | 0.52 | 0.69 |
| | Solution | | SSG () | Crospovidone () | DT (s) | WT | FB (%) | Desirability |
| | −0.36 | 0.56 | 15 | 23.58 | 0.54 | 0.942 |
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