In Vitro and In Vivo Correlation of Colon-Targeted Compression-Coated Tablets

Table 4

Summary of the intraday () and interday () precision (% CV) and accuracy (% RE) of the three levels of quality control (QC) samples.

Nominal concentration (µg/mL)	Mean observed concentration (µg/mL)	% CV	% RE
1st day ()
0.150	0.151 ± 0.0028	1.85	−0.38
20.00	19.45 ± 0.48	2.48	2.73
40.00	38.10 ± 2.41	6.31	4.76
2nd day ()
0.150	0.151 ± 0.0028	1.83	−0.47
20.00	19.53 ± 0.75	3.83	2.33
40.00	40.46 ± 1.46	3.60	−1.15
3rd day ()
0.150	0.151 ± 0.0038	2.54	−0.68
20.00	18.87 ± 1.11	5.88	5.63
40.00	38.78 ± 2.50	6.44	3.05
Interday ()
0.150	0.151 ± 0.0027	1.82	−0.51
20.00	19.29 ± 0.78	4.03	3.56
40.00	39.11 ± 2.15	5.51	2.22