Research Article
Formulation and Evaluation of Antibacterial Creams and Gels Containing Metal Ions for Topical Application
Table 5
Antimicrobial activity of the selected gel formulations in various dilutions against
Escherichia coli and
Staphylococcus aureus (
).
| Concentration of each active (%) | Zone of inhibition (mm) (mean ± SD) | G1 | G5 | E. coli | S. aureus | E. coli | S. aureus |
| 0 (blank) | 0 | 0 | 0 | 0 | 0 (paraben concentrate) | 0 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 0 | 0.25 | 8.4 ± 0.2 | 9.1 ± 0.3 | 9.2 ± 0.5 | 9.2 ± 0.17 | 0.5 | 11.4 ± 0.1 | 11.9 ± 0.5 | 12.3 ± 0.6 | 11.3 ± 0.4 | 1 | 16.5 ± 0.1 | 18.1 ± 0.9 | 16.6 ± 1.3 | 13.9 ± 0.2 | 2 | 21.9 ± 0.6 | 23.1 ± 0.2 | 21.8 ± 0.2 | 17.6 ± 0.4 | 3 | 24.9 ± 0.3 | 26.3 ± 0.4 | 24.4 ± 0.4 | 19.7 ± 0.4 | Gentamicin (control) | 22.4 ± 0.15 | 23.5 ± 0.2 | 22.7 ± 1.8 | 21.3 ± 1.2 |
|
|