Porcine Pancreatic Lipase Inhibitory Agent Isolated from Medicinal Herb and Inhibition Kinetics of Extracts from Eleusine indica (L.) Gaertner

Table 2

Yield and PPL inhibitory activity of E. indica crude methanolic extract and solvent fractions.

	Yield (g/100 g; crude extract)	PPL inhibition; (%)
Crude methanolic extract	—	25.05 ± 3.58^c
Hexane fraction	34.16 ± 7.53	27.01 ± 5.68^c
Dichloromethane fraction	0.98 ± 0.47	25.57 ± 3.26^c
Ethyl acetate fraction	1.40 ± 0.47	10.38 ± 2.73^b
Butanol fraction	9.72 ± 2.36	5.23 ± 2.29^a
Aqueous fraction	52.78 ± 4.37	4.18 ± 1.91^a
Orlistat	—	34.49 ± 5.39^d

Values are expressed as mean ± SD, values. The concentration of the tested extract against PPL was 100 μg/mL. Statistically significant effects were compared using one-way ANOVA (Tukey’s post-hoc test), where different letters in superscripts indicated significance at .