Pharmacological Investigation of the Wound Healing Activity of Cestrum nocturnum (L.) Ointment in Wistar Albino Rats

Table 2

Effect of EECN on % wound contraction and epithelialization period of wound in excision wound model.

Group	% wound contraction				Epithelialization period (days)
	4th day	8th day	12th day	16th day
Group I (untreated)	4.39 0.82	18.62 0.69	42.62 2.56	68.87 0.91	19.16 0.7
Group II (ointment base treated)	4.21 0.19	19.48 0.93	42.76 1.36	71.2 0.93	19.66 0.66
Group III (standard)	14.55 0.87; a, b	38.39 0.46; a, b, c	67.38 2.01; a, b	94.3 0.43; a, b	17.33 0.4; a, b
Group IV (2% w/w, ointment)	13.83 1.0; a, b	31.11 0.83; a, b, c	56.46 0.79; a, b, c	80.21 0.27; a, b, c	18.33 0.22
Group V (5% w/w, ointment)	14.33 0.94; a, b	34.82 0.67; a, b	59.64 1.18; a, b, c	93.58 0.76; a, b	17.66 0.7; a, b

All values are represented as mean SEM, animals in each group. Data were analyzed by one-way ANOVA, followed by Tukey-Kramer Multiple Comparisons Test. a: significant difference as compared to untreated group (group I); b: significant difference as compared to ointment base treated group (group II); c: significant difference as compared to standard group (group III), and P < 0.01, P < 0.001.