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Journal of Pharmaceutics
Table of Contents
Journal of Pharmaceutics
/
2017
/
Article
/
Tab 4
/
Research Article
Combined Effect of Synthetic and Natural Polymers in Preparation of Cetirizine Hydrochloride Oral Disintegrating Tablets: Optimization by Central Composite Design
Table 4
Response variables (
) obtained from trial formulations of CTZ ODTs.
Trial run
Croscarmellose sodium (mg) (
X
1
)
H. rosa-sinensis
mucilage (mg) (
X
2
)
Disintegration time (sec) (
Y
1
)
Friability (%) (
Y
2
)
Cumulative drug released (%) (
Y
3
)
1
5
10
22
2
10
10
17
3
15
10
16
4
5
20
15
5
10
20
12
6
15
20
14
7
5
30
16
8
10
30
18
9
15
30
20
10
10
20
13
11
10
20
12
12
10
20
12
13
10
20
12