Combined Effect of Synthetic and Natural Polymers in Preparation of Cetirizine Hydrochloride Oral Disintegrating Tablets: Optimization by Central Composite Design
Table 5
ANOVA for response surface quadratic model for responses.
Term
DT
DR
value
p value
value
p value
value
p value
Model
46.08
1.25
7.52
-CCS
1.27
0.3106
0.12
0.7457
2.46
0.1777
-HRM
1.27
0.3106
0.47
0.5235
0.77
0.4191
63.60
1.24
0.3156
8.45
19.65
0.55
0.4901
0.15
0.7184
153.39
0.000
2.05
0.2120
31.92
3.39
0.1249
0.063
0.8112
0.011
0.9192
0.000
1.0000
0.49
0.5154
0.82
0.4075
gives an indication of the significance of an effect .