Combined Effect of Synthetic and Natural Polymers in Preparation of Cetirizine Hydrochloride Oral Disintegrating Tablets: Optimization by Central Composite Design

Table 6

Optimization of CTZ ODTs formulation by surface response method.

	Constraints
Name	Goal	Lower limit	Upper limit
CCS	In range	−1	1
HRM	In range	−1	1
DT (sec)	In range	12	14
(%)	In range	0.29	0.5
DR in 25 minutes	In range	99.0	101.32