Research Article

Cocoa Pod Husk Pectin Intended as a Pharmaceutical Excipient Has No Adverse Effects on Haematological Parameters in Sprague Dawley Rats

Table 3

Results showing the effect of CPH pectin on red blood cell indices for female rats.

Red blood cell indicesDayControlLow dose
0.714 mg/kg
Medium dose
7.14 mg/kg
High dose
71.4 mg/kg

RBC (x 106/ul)308.13±0.108.36±0.187.72±0.198.25±0.11
607.77±0.068.15±0.157.96±0.147.88±0.14
908.08±0.108.14±0.218.14±0.178.26±0.12

HGB (g/dl)3015.40±0.1214.57±0.2314.20±0.2614.98±0.08
6014.95±0.1314.87±0.2714.27±0.2914.62±0.15
9015.18±0.1914.72±0.2814.82±0.2315.18±0.19

HCT (%)3043.80±0.4742.88±0.4041.42±0.8643.48±0.40
6042.75±0.3943.95±0.6941.97±0.6042.83±0.54
9044.30±0.9443.87±0.8744.22±0.6844.97±0.65

MCV (fl)3053.85±0.6152.35±0.3553.70±0.5452.73±0.39
6054.97±0.2653.93±0.3654.23±0.4454.37±0.50
9054.72±0.6153.97±0.6854.32±0.4054.42±0.38

MCH (g/dl)3018.95±0.1417.78±0.1518.38±0.1818.15±0.17
6019.23±0.1018.23±0.2117.96±0.5018.58±0.21
9018.82±0.1218.10±0.2618.20±0.1618.38±0.13

MCHC (g/dl)3034.97±0.3034.48±0.2634.67±0.1834.80±0.18
6034.55±0.1234.00±0.1434.32±0.2034.12±0.16
9034.37±0.2033.63±0.0933.82±0.2233.83±0.07

RDW-SD (fl)3026.00±0.1826.22±0.2325.98±0.2125.98±0.13
6026.68±0.1626.72±0.2226.62±0.2326.62±0.23
9026.58±0.2026.58±0.1226.75±0.5926.16±0.10

RDW-CV (%)3011.53±0.2511.37±0.2411.50±0.7910.95±0.15
6011.50±0.2611.70±0.2512.25±0.9211.37±0.21
9011.35±0.3111.67±0.0911.93±0.8911.17±0.44