Research Article
Cocoa Pod Husk Pectin Intended as a Pharmaceutical Excipient Has No Adverse Effects on Haematological Parameters in Sprague Dawley Rats
Table 3
Results showing the effect of CPH pectin on red blood cell indices for female rats.
| Red blood cell indices | Day | Control | Low dose 0.714 mg/kg | Medium dose 7.14 mg/kg | High dose 71.4 mg/kg |
| RBC (x 106/ul) | 30 | 8.13±0.10 | 8.36±0.18 | 7.72±0.19 | 8.25±0.11 | 60 | 7.77±0.06 | 8.15±0.15 | 7.96±0.14 | 7.88±0.14 | 90 | 8.08±0.10 | 8.14±0.21 | 8.14±0.17 | 8.26±0.12 |
| HGB (g/dl) | 30 | 15.40±0.12 | 14.57±0.23 | 14.20±0.26 | 14.98±0.08 | 60 | 14.95±0.13 | 14.87±0.27 | 14.27±0.29 | 14.62±0.15 | 90 | 15.18±0.19 | 14.72±0.28 | 14.82±0.23 | 15.18±0.19 |
| HCT (%) | 30 | 43.80±0.47 | 42.88±0.40 | 41.42±0.86 | 43.48±0.40 | 60 | 42.75±0.39 | 43.95±0.69 | 41.97±0.60 | 42.83±0.54 | 90 | 44.30±0.94 | 43.87±0.87 | 44.22±0.68 | 44.97±0.65 |
| MCV (fl) | 30 | 53.85±0.61 | 52.35±0.35 | 53.70±0.54 | 52.73±0.39 | 60 | 54.97±0.26 | 53.93±0.36 | 54.23±0.44 | 54.37±0.50 | 90 | 54.72±0.61 | 53.97±0.68 | 54.32±0.40 | 54.42±0.38 |
| MCH (g/dl) | 30 | 18.95±0.14 | 17.78±0.15 | 18.38±0.18 | 18.15±0.17 | 60 | 19.23±0.10 | 18.23±0.21 | 17.96±0.50 | 18.58±0.21 | 90 | 18.82±0.12 | 18.10±0.26 | 18.20±0.16 | 18.38±0.13 |
| MCHC (g/dl) | 30 | 34.97±0.30 | 34.48±0.26 | 34.67±0.18 | 34.80±0.18 | 60 | 34.55±0.12 | 34.00±0.14 | 34.32±0.20 | 34.12±0.16 | 90 | 34.37±0.20 | 33.63±0.09 | 33.82±0.22 | 33.83±0.07 |
| RDW-SD (fl) | 30 | 26.00±0.18 | 26.22±0.23 | 25.98±0.21 | 25.98±0.13 | 60 | 26.68±0.16 | 26.72±0.22 | 26.62±0.23 | 26.62±0.23 | 90 | 26.58±0.20 | 26.58±0.12 | 26.75±0.59 | 26.16±0.10 |
| RDW-CV (%) | 30 | 11.53±0.25 | 11.37±0.24 | 11.50±0.79 | 10.95±0.15 | 60 | 11.50±0.26 | 11.70±0.25 | 12.25±0.92 | 11.37±0.21 | 90 | 11.35±0.31 | 11.67±0.09 | 11.93±0.89 | 11.17±0.44 |
|
|