Table of Contents
Journal of Polymers
Volume 2013 (2013), Article ID 938726, 8 pages
http://dx.doi.org/10.1155/2013/938726
Review Article

Pharmaceutical Properties and Applications of a Natural Polymer from Grewia mollis

Biomaterials and Drug Delivery Research Group, Faculty of Pharmaceutical Sciences, University of Jos, PMB 2084, Jos 930001, Nigeria

Received 22 March 2013; Accepted 16 June 2013

Academic Editor: Alain Durand

Copyright © 2013 Elijah I. Nep et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The use of naturally occurring biocompatible materials has been the focus of recent research activity in the design of dosage forms for immediate and controlled release formulations. Grewia gum is an intracellular gum obtained by extraction from the inner stem bark of the shrub Grewia mollis (Malvaceae). It grows abundantly (wild or cultivated) in the middle belt region of Nigeria, and the mucilage has been used by indigenes of this belt as thickener in soups. Grewia gum has been investigated for potential applications in pharmaceutical dosage forms. The industrial extrapolation of the applications of the gum has, however, been slowed by the limited structural, toxicological, and stability data available on the gum. This paper highlights ethnobotanical uses of G. mollis shrub and discusses the structural features, functional properties, and applications of grewia gum with emphases on its pharmaceutical potentials.