Review Article
Posttranslational Processing and Modification of Cathepsins and Cystatins
Table 4
Contribution of cathepsin L or B on bone resorption.
| Inhibitors (10-6M) | | Cathepsin L | Cathepsin B | Bone resorption | |
| Control | | 100 | 100 | 100 | % | Pepstatin | − | 103 | 104 | 104 | % | CA-074 | − | 100 | 2.2 | 94 | % | E-64 | + | 10 | 2 | 40 | % | Cystatin α | + | 3.1 | 4.3 | 18 | % | Chymostatin | + | 9.8 | 101 | 6 | % | CA-148 | + | 0 | 100 | 0 | % |
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