Suppression by Ghrelin of Porphyromonas gingivalis-Induced Constitutive Nitric Oxide Synthase S-Nitrosylation and Apoptosis in Salivary Gland Acinar Cells

Figure 4

Effect of ghrelin on P. gingivalis LPS-induced expression of cNOS activity in sublingual salivary gland acinar cells. The cells, preincubated with the indicated concentrations of ghrelin, were treated with the LPS at 100 ng/mL and incubated for 16 hours. Values represent the means $\pm$ SD of five experiments. ${}_{}{}^{*}P<.05$ compared with that of control. ${}_{}{}^{**}P<.05$ compared with that of LPS alone.