Mos in the Oocyte: How to Use MAPK Independently of Growth Factors and Transcription to Control Meiotic Divisions

<table>Meiotic arrest of the unfertilized oocyte: the downstream effectors of Mos/MAPK. In all species, oocytes halt meiosis to prevent embryonic development in the absence of fertilization. Depending on species, meiosis arrests at prophase I, metaphase I, metaphase II, or G1 following meiosis. Except in <i>C. elegans</i>, Mos was found to be the ubiquitous cytostatic factor responsible for the unfertilized oocyte arrest. Its downstream targets accounting for the meiotic arrest of the unfertilized oocytes are indicated.</table>

Journal of Signal Transduction

fig3

Figure 3

Figure 3: Mos in the Oocyte: How to Use MAPK Independently of Growth Factors and Transcription to Control Meiotic Divisions 