The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries

<table>Key signalling pathways targeted with our divergent targeting strategy. The multitargeted approach includes activating SSTRs, inhibiting ErbB1, and inducing DNA damage. Key proteins analysed in this study are circled, while pathways not investigated are represented by dotted lines.</table>

Journal of Signal Transduction

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Scheme 2

Scheme 2: The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries 

Scheme 2 | The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial Mimicries 