Signal Transduction in Astrocytes during Chronic or Acute Treatment with Drugs (SSRIs, Antibipolar Drugs, GABA-ergic Drugs, and Benzodiazepines) Ameliorating Mood Disorders
Figure 10
Uptake of [3H]myo-inositol at concentrations of 25, 40, and 50 μM during 60 min in U251 MG astrocytoma cells treated with 1 mM lithium chloride for 2 weeks before the uptake experiment as well as during the uptake (filled columns) and in untreated control cultures (open columns). Note lithium-induced decrease of uptake at 50 μM myo-inositol versus increase at 25 μM. SEM values are shown by vertical bars. *Statistically significant difference between lithium-treated and control cultures (), from Wolfson et al. [88].
