Research Article

Trichomonas vaginalis Incidence Associated with Hormonal Contraceptive Use and HIV Infection among Women in Rakai, Uganda

Table 2

(a) T. vaginalis incidence by demographic and behavioral characteristics (HC or condom use). (b) T. vaginalis incidence by demographic and behavioral characteristics (type of contraception used). (c) T. vaginalis incidence by demographic and behavioral characteristics (consistency of contraceptive use at baseline and follow-up). (d) T. vaginalis incidence by demographic and behavioral characteristics (consistency of HC methods used).
(a)

Incident T. vaginalis /PYIncidence/100 pyUnadj.IRR 95% CIAdj.IRR 95% CI

Overall237496/3924.62.4
 HC use in last 12 months
  No HC/no condom 105445/1733.22.601.001.00
  HC82924/1366.21.80.68 (0.41–1.11)0.71 (0.43–1.17)
  Condoms only49127/825.23.31.3 (0.78–2.03)0.98 (0.58–1.67)
 Age
  <2016511/277.74.01.001.00
  20–2993940/1566.32.60.64 (0.33–1.26)0.71 (0.35–1.44)
  30–3995137/1565.82.40.60 (0.30–1.17)0.58 (0.28–1.18)
  40+3198/514.81.60.39 (0.16–0.98)*0.29 (0.11–0.74)*
 Marital status
  Currently married188769/3106.72.21.00
  Previously married27514/459.83.01.37 (0.77–2.43)
  Never married21213/358.03.61.63 (0.90–2.96)
 Education
  None1028/172.34.61.001.00
  Primary142667/2359.22.80.61 (0.29–1.27)0.64 (0.30–1.34)
  Secondary or more84621/1393.01.50.32 (0.14–0.73)**0.32 (0.14–0.74)**
 Nonmarital sexual partners in last 12 months
  0183564/3016.52.11.001.00
  150630/851.73.51.66 (1.07–2.56)**1.44 (0.89–2.33)
  2+332/56.43.51.67 (0.41–6.83)1.28 (0.30–5.41)
 Social-economic status
  High131150/2200.82.31.00
  Middle72228/1165.42.41.06 (0.66–1.68)
  Low34118/558.43.21.42 (0.83–2.43)
 Nugent score
  Normal109342/1795.42.31.001.00
  Intermediate3396/544.21.10.47 (0.20–1.11)0.46 (0.20–1.09)
  BV94248/1585.03.01.29 (0.86–1.96)1.13 (0.74–1.72)
 HIV status
  Negative206969/3387.42.01.001.00
  Positive30527/5375.02.47 (1.58–3.85)**2.34 (1.44–3.78)**
 Syphilis serology
  Negative230092/3802.62.41.001.00
  Positive744/122.03.31.36 (0.50–3.69)1.09 (0.39–3.01)

. ** .
(b)

Incident T. vaginalis /PYIncidence/100 pyUnadj.IRR 95% CIAdj.IRR 95% CI

Overall237496/3924.62.4
 HC use in last 12 months
  No HC/no condom 105445/1733.22.601.001.00
  DMPA only66415/1089.91.40.53 (0.30–0.95)*0.54 (0.30–0.98)*
  COC only1335/220.32.30.87 (0.35–2.20)1.02 (0.40–2.59)
  Implants only324/56.07.12.75 (1.00–7.65)*3.01 (1.07–8.49)*
  Condoms only49127/825.23.31.2 (0.78–2.03)0.97 (0.57–1.64)
 Age
  <2016511/277.74.01.001.00
  20–2993940/1566.32.60.64 (0.33–1.26)0.70 (0.34–1.43)
  30–3995137/1565.82.40.60 (0.30–1.17)*0.57 (0.30–1.16)
  40+3198/514.81.60.39 (0.16–0.98)**0.28 (0.11–0.73)**
 Education
  None1028/172.34.61.001.00
  Primary142667/2359.22.80.610 (0.29–1.27)0.63 (0.30–1.32)
  Secondary or more84621/1393.01.50.32 (0.14–0.73)**0.32 (0.14–0.74)**
 Nonmarital sexual partners in last 12 months
  0183564/3016.52.11.001.00
  150630/851.73.51.66 (1.07–2.56)1.49 (0.92–2.42)
  2+332/56.43.51.67 (0.41–6.83)1.26 (0.30–5.28)
 Social-economic status
  High131150/2200.82.31.00
  Middle72228/1165.42.41.06 (0.66–1.68)
  Low34118/558.43.21.41 (0.83–2.43)
 Nugent score
  Normal109342/1795.42.31.001.00
  Intermediate3396/544.21.10.47 (0.20–1.11)0.44 (0.19–1.05)
  BV94248/1585.03.01.29 (0.86–1.96)1.10 (0.72–1.69)
 HIV status
  Negative206969/3387.42.01.001.00
  Positive30527/5375.02.40 (1.42–4.08)**2.38 (1.47–3.86)**
 Syphilis serology
  Negative230092/3802.62.41.001.00
  Positive744/122.03.31.36 (0.50–3.69)1.16 (0.42–3.20)

. ** .
(c)

Incident T. vaginalis /PYIncidence/100 pyUnadj.IRR 95% CIAdj.IRR 95% CI

Overall237496/3924.62.4
 HC use at baseline and follow-up
  Consistently used no method65330/1071.72.81.001.00
  Consistently used HC48315/789.11.90.68 (0.36–1.26)0.73 (0.39–1.40)
  Initiated HC use at follow-up2449/402.72.20.80 (0.38–1.68)0.76 (0.36–1.69)
  Discontinued HC use at follow-up2153/350.60.860.30 (0.09–1.00)*0.30 (0.09–0.99)*
  Consistently used condoms21712/365.93.21.17 (0.60–2.29)0.87 (0.42–1.79)
  Others56227/944.52.81.02 (0.61–1.71)0.81 (0.47–1.40)
 Age
  <2016511/277.74.01.001.00
  20–2993940/1566.32.60.64 (0.33–1.26)0.71 (0.35–1.44)
  30–3995137/1565.82.40.60 (0.30–1.17)0.58 (0.28–1.17)
  40+3198/514.81.60.39 (0.16–0.98)**0.28 (0.11–0.72)**
 Education
  None1028/172.34.61.001.00
  Primary142667/2359.22.80.610 (0.29–1.27)0.68 (0.32–1.43)
  Secondary or more84621/1393.01.50.32 (0.14–0.73)*0.34 (0.14–0.78)*
 Nonmarital sexual partners in last 12 months
  0183564/3016.52.11.001.00
  150630/851.73.51.66 (1.07–2.56)1.47 (0.92–2.36)
  2+332/56.43.51.67 (0.41–6.83)1.29 (0.31–5.37)
 Social-economic status
  High131150/2200.82.31.00
  Middle72228/1165.42.41.06 (0.66–1.68)
  Low34118/558.43.21.41 (0.83–2.43)
 Nugent score
  Normal109342/1795.42.31.001.00
  Intermediate3396/544.21.10.47 (0.20–1.11)0.46 (0.19–1.08)
  BV94248/1585.03.01.29 (0.86–1.96)1.14 (0.74–1.73)
 HIV Status
  Negative206969/3387.42.01.001.00
  Positive30527/5375.02.40 (1.42–4.08)**2.36 (1.44–3.85)**
 Syphilis serology
  Negative230092/3802.62.41.001.00
  Positive744/122.03.31.36 (0.50–3.69)1.07 (0.39–2.94)

. ** .
(d)

Incident T. vaginalis /PYIncidence/100 pyUnadj.IRR 95% CIAdj.IRR 95% CI

Overall237496/3924.62.4
 HC use at baseline and follow-up
  Consistently used no method65330/1071.72.81.001.00
  Consistently used DMPA3599/582.91.50.55 (0.26–1.16)0.59 (0.28–1.26)
  Consistently used COCs502/84.22.40.85 (0.20–3.55)1.07 (0.25–4.56)
  Consistently used implants284/49.88.02.87 (1.01–8.14)*3.13 (1.08–9.07)*
  Other categories128451/2135.82.40.85 (0.54–1.34)0.70 (0.44–1.13)
 Age
  <2016511/277.74.01.001.00
  20–2993940/1566.32.60.64 (0.33–1.26)0.65 (0.32–1.31)
  30–3995137/1565.82.40.60 (0.30–1.17)0.52 (0.26–1.06)
  40+3198/514.81.60.39 (0.16–0.98)**0.26 (0.10–0.67)**
 Education
  None1028/172.34.61.001.00
  Primary142667/2359.22.80.610 (0.29–1.27)0.64 (0.30–1.38)
  Secondary or more84621/1393.01.50.32 (0.14–0.73)0.34 (0.14–0.78)*
 Nonmarital sexual partners in last 12 months
  0183564/3016.52.11.001.00
  150630/851.73.51.66 (1.07–2.56)1.61 (1.01–2.55)*
  2+332/56.43.51.67 (0.41–6.83)1.40 (0.33–5.77)
 Social-economic status
  High131150/2200.82.31.00
  Middle72228/1165.42.41.06 (0.66–1.68)
  Low34118/558.43.21.41 (0.83–2.43)
 Nugent score
  Normal109342/1795.42.31.001.00
  Intermediate3396/544.21.10.47 (0.20–1.11)0.45 (0.19–1.06)
  BV94248/1585.03.01.29 (0.86–1.96)1.09 (0.71–1.66)
 HIV status
  Negative206969/3387.42.01.001.00
  Positive30527/5375.02.40 (1.42–4.08)2.52 (1.56–4.08)**
 Syphilis serology
  Negative230092/3802.62.41.001.00
  Positive744/122.03.31.36 (0.50–3.69)1.07 (0.39–2.95)

. ** .