Table of Contents
Journal of Thermodynamics
Volume 2009, Article ID 186723, 10 pages
Research Article

Entropy Generation and Human Aging: Lifespan Entropy and Effect of Diet Composition and Caloric Restriction Diets

Department of Mechanical Engineering, Texas A&M University, 3123 TAMU, College Station, TX 77843-3123, USA

Received 21 January 2009; Accepted 23 June 2009

Academic Editor: Ali Akbar Saboury

Copyright © 2009 Carlos A. Silva and Kalyan Annamalai. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The first and second laws of thermodynamic were applied to statistical databases on nutrition and human growth in order to estimate the entropy generation over the human lifespan. The calculations were performed for the cases of variation in the diet composition and calorie restriction diets; and results were compared to a base case in which lifespan entropy generation was found to be 11 404 kJ/K per kg of body mass, predicting a lifespan of 73.78 and 81.61 years for the average male and female individuals respectively. From the analysis of the results, it was found that changes of diet % of fat and carbohydrates do not have a significant impact on predicted lifespan, while the diet % of proteins has an important effect. Reduction of diet protein % to the minimum recommended in nutrition literature yields an average increase of 3.3 years on the predicted lifespan. Changes in the calorie content of the diet also have an important effect, yielding a % increase in lifespan equal or higher than the % reduction in the diet caloric content. This correlates well experimental data on small mammal and insects, in which lifespan has been increased by diet restriction.