Research Article

Analogs of LDL Receptor Ligand Motifs in Dengue Envelope and Capsid Proteins as Potential Codes for Cell Entry

Table 2

Receptor ligand and NLS motifs in the dengue virus envelope proteins.

Envelope proteinsΨBΨXBMonoBipartite

Potential receptor ligand and nuclear localization signal motifs
DENV2 
LRMDK
FKIVK
LKCRLRM 
MRGAKRM
KKGSSIGQMFETTMRGAKR
Dsp2EP     0564KCRLRMDKLQLKGMSYSMCTGKFKIVKEIAET-K-FITC
Dsp2EP (B)0558GHLKCRLDMDDLQLKGMSYSMCTGKFKIVKEIAETQHG-K-FITC
Dsp2EP (C)0558GHLKCRLRMDKLQLKGMSYSMCTGKFDIVDEIAETQHG-K-FITC

Receptor ligand motifs in Dsp2EP, Apo E and Apo B100
DENV2EP0563LKCRLRMDKLQLKG-MSYSMCTGKFKIVKEIAET0595
Apo E0067TMKELKAYKSELEEQLTPVAEETRARLSKELQAA0100
Apo B1003176FDRHFEKNRNNALDFVTKSYNETKIKFDKYKAEK3209
Apo B1003181EKNRNNALDFVTKSYNETKIKFDKYKAEKSHDEL3214
Apo B1002604NFKDLKNIKIPSRFSTP(X18)EMKVKIIRTIDQM2651