Effects of Experimental Sarcocystis neurona-Induced Infection on Immunity in an Equine Model

Figure 1

Experimental design for S. neurona infection study. Following a 2-week acclimation, nine horses had baseline neurologic examinations, immune function analysis, and CSF taps with samples submitted for SnSAG1 analysis. Horses were randomly assigned to either control or S. neurona experimentally infected treatment groups. Peripheral blood was collected on day −5, day −1, days 0–10, day 14, day 21, day 28, day 35, day 42, day 56, and day 70 for infection or immune function assays. CSF taps (A/O = atlanto-occipital space) were performed on day 5 and postinfection day 73.