Tamoxifen Promotes Axonal Preservation and Gait Locomotion Recovery after Spinal Cord Injury in Cats

Figure 2

Representative T13-L1 microscopy images stained with H&E in coronal cuts (20 μm thick) and schematic illustrations showing the lesion extension size. (a) Schematic diagram T13-L1 segment; (b) schematic diagram illustrating the lesion extension size for each one of the three cats injured without tamoxifen group; black continuous line represents cat 1, red circular dotted line cat 2, and blue oval dotted line cat 3; (c) schematic diagram showing lesions extensions in each one of the cats in the injured with tamoxifen group, lines as indicated. (d) Spinal cord coronal cut from an intact cat. (e) Spinal cord coronal cut from an injured cat without tamoxifen. (f) Spinal cord cut from an injured cat with tamoxifen; scale bar: 500 μm.

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