Tamoxifen Promotes Axonal Preservation and Gait Locomotion Recovery after Spinal Cord Injury in Cats

Figure 5

Microscopy images of FOX-3/DAPI positive cells in the dorsal horn, periaqueductal zone, and ventral horn, at T13-L1 spinal cord injury site. Dorsal horn neurons: ((b) and (c)) ipsilateral side, ((d) and (e)) contralateral side: (a) intact cat, (b) injured untreated cat, (c) injured treated cat, (d) injured untreated cat, and (e) injured treated cat. Periaqueductal Zone Neurons: ((g) and (h)) ipsilateral side and ((i) and (j)) contralateral side. (f) Intact cat, (g) injured cat without tamoxifen, (h) injured cat with tamoxifen, (i) injured cat without tamoxifen, and (j) injured cat with tamoxifen. Neurons in the ventral horn: ((l) and (m)) ipsilateral side and ((n) and (o)) contralateral side. (k) Intact cat, (l) injured cat without tamoxifen, (m) injured cat with tamoxifen, (n) injured cat without tamoxifen, and (o) injured cat with tamoxifen, scale bar 150 μm; FOX-3 neurons in green, cell nuclei in blue.