Research Article
Tamoxifen Promotes Axonal Preservation and Gait Locomotion Recovery after Spinal Cord Injury in Cats
Table 1
Number of FOX-3/DAPI positive cells.
| | Site | Ipsilateral | Contralateral | | INT | IWOT | IWT | INT | IWOT | IWT | DH
| PAZ
| VH
| DH
| PAZ
| VH
| DH
| PAZ
| VH
| DH
| PAZ
| VH
| DH
| PAZ
| VH
| DH
| PAZ
| VH
|
| | 200 µm RFI | 59 ± 1 | 33.8 ± 1.4 | 15.9 ± 0.1 | 34.7 ± 6.3 | 12.5 ± 2.1 | 6.3 ± 1.2 | 58.7 ± 8 | 17 ± 1.6 | 13.1 ± 3 | 58 ± 0.5 | 32.1 ± 1.3 | 15 ± 1 | 38.5 ± 2.3 | 4 ± 2.3 | 6.2 ± 1.5 | 60.4 ± 10.2 | 4.9 ± 2.8 | 11.8 ± 3.4 |
| | IS | 62.3 ± 0.8 | 32.4 ± 1.2 | 15.4 ± 1.1 | 33.6 ± 10.5 | 10.3 ± 2.4 | 5.3 ± 1.7 | 48.5 ± 11.9 | 13.72 ± 4.4 | 12.8 ± 2.5 | 63.1 ± 1 | 31.4 ± 1.6 | 16 ± 0.8 | 39.9 ± 10.4 | 16 ± 8.4 | 5.5 ± 0.6 | 46.2 ± 12 | 14.9 ± 2.5 | 12.6 ± 3.1 |
| | 200 µm CFI | 58.6 ± 1.2 | 33.5 ± 1.1 | 16 ± 0.4 | 41.1 ± 4.4 | 15.5 ± 5.3 | 6.7 ± 0.7 | 50.3 ± 9.5 | 13.1 ± 6.1 | 11.7 ± 4.7 | 61 ± 0.6 | 33.1 ± 2 | 17 ± 1 | 50.1 ± 8.8 | 16.4 ± 4 | 7.2 ± 0.8 | 57.8 ± 5.5 | 13.4 ± 4.7 | 12.7 ± 4 |
|
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INT, intact; IWOT, injured without tamoxifen; IWT, injured with tamoxifen; DH, dorsal horn; PAZ, periaqueductal zone; VH, ventral horn; RFI, rostral from injury; IS, injury site; CFI, caudal from injury.
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