Subcutaneous Implants of a Cholesterol-Triglyceride-Buprenorphine Suspension in Rats

Table 3

Mean effects of drug on tail flick measurements at 55°C in female rats.

Dose	Time (days)
	1	2	3	4	5
	Thermal latency in seconds
Control	4.7 ± 2.0	6.5 ± 1.2	7.8 ± 1.5	7.1 ± 0.4	6.0 ± 0.9
0.65 mg/kg	16 ± 2.0	27 ± 7.6	24 ± 2.3	22 ± 6.3	19.4 ± 2.9
1.3 mg/kg	13 ± 6.8	26 ± 6.0	27 ± 14	25 ± 7.4	17.6 ± 4.1

for drug versus vehicle group, .