Review Article
Probiotics for the Control of Helminth Zoonosis
Table 1
Probiotic strains used against Schistosoma mansoni infection in mice.
| Probiotics strain | Dose/route | Mechanisms | Antiparasitic effect | References |
| Zymomonas mobilis | 1 × 109 CFU/mL orally, at a dose of 0.3 mL/day | Provoke a secondary immune response | A 61% protection from the infection was observed in the treated group | [17] |
| Probiotic labneh containing streptococcus salivarius subsp. thermophilus, Lactobacillus delbrueckii subsp. Bulgaricus and DVS-ABT2 | Probiotic labneh and garlic and onions fed for 21 days before and 45 days after infection | Improving intestinal balance | 50%–66% reduction in worm burden; 70% and 56.44% egg count reduction in liver and intestine, respectively | [18] |
| Lactobacillus casei B-444; Lactobacillus plantarum B-531; Lactobacillus reuteriB-14141 and Lactobacillus acidophilus | 1 × 106 CFU each mixed with feed | A significant stimulation for IgM response against SWAP before and after infection | Increased IgM; A decrease in the activity of AST, LDH and GT | [19] |
| Lactobacillus sporogenes | 12.5 million spores/mice/week for 8 weeks orally | Decreased cytokine-induced chromosomal aberrations and DNA damage | Significant reduction in chromosomal aberrations | [20] |
| Lactobacillus sporogenes | 12.5 million spores/mice/week for 8 weeks orally from the first day of infection | Reduced DNA damage; ameliorates the hepatic and intestinal damage | Reduced worm and egg count | [21] |
|
|
SWAP: soluble worm antigen preparation, AST: aspartate transaminase, ALT: alanine transaminase, LDH: lactate dehydrogenase, γGT: gamma-glutamyl transferase, DVS-ABT2: containing Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium bifidum, and CFU: colony forming units.
|