Probiotics for the Control of Helminth Zoonosis

Table 2

Effects of different strains of probiotics on Trichinella spiralis in mice model.

Probiotics strain	Dose/route	Mechanisms	Antiparasitic effect	References
Lactobacillus acidophilus P110, Lactobacillus plantarum P164 and Lactobacillus casei ATCC 7469	1.0 ml/kg/day with a concentration of 1.9 × 10^9 CFU/ml orally	Both showed higher levels of IFN-	60.98%, 87.92% and 74.88% larval count reduction, respectively	[7]
Enterococcus faecium AL41, Enterococcus durans ED26E/7, Lactobacillus fermentum AD1 and Lactobacillus plantarum 17L/1	10^9 CFU/ml in 100 μl orally	Stimulated phagocytosis and respiratory burst of blood PMNL; and high intensity of enzymatic stimulation	Protective effect was induced by all strains, the highest reduction by E. faecium AL41	[8]
L. casei strain ATCC 469	1.9 × 10^9 CFU/ml orally	Reduced invasion of larvae into the host	Significant protective response	[31]
Lactobacillus casei	Intraperitoneal	Higher levels of IgG and IgA anti-T. spiralis and IL-4, but lower levels of IFN-	78.6%–100% protection	[30]
Lactobacillus casei Shirota strain (LcS)	Intraperitoneal	IgA anti-T. spiralis levels were higher	Induces protection against T. spiralis	[32]

PMNL: polymorphonuclear leukocytes.