Review Article
Probiotics for the Control of Helminth Zoonosis
Table 3
Probiotic strains used against Ascaris suum in pig model.
| Probiotics strain | Dose/route | Mechanisms | Antiparasite effect | References |
| Lactobacillus rhamnosus (LGG) | 1 × 1010 CFU/day orally | Induced an increase in toll-like receptor- (TLR-) 9 and tumor necrosis factor- (TNF-) gene expression in AM | Reduced Ascaris suum-induced eosinophil activity in TBLNs | [70] |
| Lactobacillus rhamnosus HN001 (HN001) | 1 × 1010 CFU/day orally | Increased in IFN- expression and regulatory (IL-10) cytokine expression | Decreased the severity of allergic skin and lung responses | [69] |
| Bifidobacterium lactis subspecies animalis (Bb12) | 3.5 × 1010 CFU orally | Increased mRNA expression of genes, including IL-25, but did not affect intestinal permeability | Did not interfere with normal expulsion of L4 from the jejunum | [68] |
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AM: alveolar macrophages and TBLNs: tracheobronchial lymph nodes.
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