Research Article

Suspected Lonely Mouse Syndrome as a Cage Effect in a Drug Safety Study

Table 2

Variability of ocular scores for drug-free (Control) animals in Trials 1 and 2.

Ocular scoreTrial 1 Trial 2

NOA: number (%)82 (85.4)104 (72.2)
Eyes closed: number (%)13 (13.6)40 (27.8)
Crusty secretions: number (%)1 (1.0)0 (0)

; no observed abnormalities.