Table of Contents
Laser Chemistry
Volume 10, Issue 5-6, Pages 455-464

UV Photoablation of Atherosclerotic Lesions. Application in Cardiology

1Laboratoire de Physique des Lasers, Universite Paris XIII, Villetaneuse 93430, France
2H.I.A. du Val de Grâce-74, Bd de Port Royal, Paris 75005, France

Received 21 March 1990; Accepted 5 April 1990

Copyright © 1990 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Various methods for the ablation of the atherosclerotic material that fills the coronary arteries are under investigation. Among them laser coronary angioplasty is one of the most promising. In this paper we show that the XeCl excimer laser (308 nm) offers many advantages which make it appear as a rather good tool. In vitro studies demonstrate the ability of precise control of the UV photoablation process, there is no thermal damage and the risk of perforation is reduced. A suitable laser-fiber optic delivery system has been developed and the results of the first in vivo procedures are very encouraging.