Research Article

Prognostic Factors in Advanced Non-Small-Cell Lung Cancer Patients: Patient Characteristics and Type of Chemotherapy

Table 1

Characteristics and univariate analysis of prognostic factors in treated NSCLC patients ( ).

CharacteristicN
(total = 270)
Median survival
(months)
Log-rank test
P-value

Age (years)
 ≤601088.6 .016
 <601628.0

Sex
 Male2288.2 .59
 Female428.3

PS
 02438.3 .25
 1 + 2276.7

Histology
 Adenocarcinoma1528.4 .31
 Others1188.1

Stage
 IIIB1711.2 .075
 IV2538.1

Smoking status
 Current2098.1 .79
 Never/former618.59

Hb
 ≥122198.1 .41
 <125110.2

FEV1
 ≥2L1289.2 .03
 < 2L1138.0

Weight loss
 No1908.2 .89
 Yes498.3

Sites of metastasis
 Single organ1918.7 .68
 Two or more798.2

Type of chemotherapy
 Platinum/Docetaxel1838.9 <.0001
 Platinum based doublet667.1
 Docetaxel monotherapy217.0

Abbreviations: PS: performance status; Hb: hemoglobin level in g/dL; FEV1: forced expiratory volume in one second.