Research Article
Prognostic Factors in Advanced Non-Small-Cell Lung Cancer Patients: Patient Characteristics and Type of Chemotherapy
Table 1
Characteristics and univariate analysis of prognostic factors in treated NSCLC patients (
).
| Characteristic | N (total = 270) | Median survival (months) | Log-rank test P-value |
| Age (years) | | | | ≤60 | 108 | 8.6 |
.016 | <60 | 162 | 8.0 |
| Sex | | | | Male | 228 | 8.2 |
.59 | Female | 42 | 8.3 |
| PS | | | | 0 | 243 | 8.3 |
.25 | 1 + 2 | 27 | 6.7 |
| Histology | | | | Adenocarcinoma | 152 | 8.4 |
.31 | Others | 118 | 8.1 |
| Stage | | | | IIIB | 17 | 11.2 |
.075 | IV | 253 | 8.1 |
| Smoking status | | | | Current | 209 | 8.1 |
.79 | Never/former | 61 | 8.59 |
| Hb | | | | ≥12 | 219 | 8.1 |
.41 | <12 | 51 | 10.2 |
| FEV1 | | | | ≥2L | 128 | 9.2 |
.03 | < 2L | 113 | 8.0 |
| Weight loss | | | | No | 190 | 8.2 |
.89 | Yes | 49 | 8.3 |
| Sites of metastasis | | | | Single organ | 191 | 8.7 |
.68 | Two or more | 79 | 8.2 |
| Type of chemotherapy | | | | Platinum/Docetaxel | 183 | 8.9 |
<.0001 | Platinum based doublet | 66 | 7.1 | Docetaxel monotherapy | 21 | 7.0 |
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Abbreviations: PS: performance status; Hb: hemoglobin level in g/dL; FEV1: forced expiratory volume in one second.
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