Simple and Objective Prediction of Survival in Patients with Lung Cancer: Staging the Host Systemic Inflammatory Response

Table 4

The relationship between parameters and survival in patients with mGPS = 0 (𝑛=213).

Parameter	Patients	Univariate		Multivariate
	𝑁	HR (95% CI)	𝑃 value	HR (95% CI)	𝑃 value
Age
<60/60–69/70–79/≥80 years	33/71/89/28	1.16 (0.98–1.37)	0.077	—
Sex
Male	115	1	—	—	—
Female	108	0.81 (0.61–1.09)	0.169	—	—
Centre
Aberdeen	98	1	0.068	—	—
Fife	10	2.72 (1.40–5.29)	—	—	—
Stobhill	77	1.00 (0.72–1.41)	—	—	—
Inverclyde	38	1.13 (0.75–1.70)	—	—	—
Deprivation (most deprived = 1, least deprived = 5)
1/2/3/4/5	68/24/71/39/21	0.94 (0.85–1.05)	0.299	—	—
Smoking history (NS = never smoker, otherwise pack years)
NS/<20/20–60/>60	21/24/126/37	0.93 (0.77–1.12)	0.467	—	—
Performance status
0/1/2/3/4	42/96/60/22/3	1.76 (1.47–2.11)	<0.001	1.69 (1.39–2.06)	<0.001
Weight loss (% body weight)
0/<5/5–10/>10	147/24/12/38	1.21 (1.08–1.37)	0.002	1.18 (1.04–1.33)	0.009
FEV1 (%)
>80/80–60/59–40/<40	138/31/45/7	0.94 (0.80–1.12)	0.515	—	—
Local symptoms
No/yes	36/127	1.38 (0.91–2.09)	0.124	—	—
Stage
NSCLC
I/II/IIIa/IIIb/IV	32/11/7/38/38	1.38 (1.25–1.53)	<0.001	1.06 (1.01–1.23)	0.017
SCLC
Limited/extensive	13/21	1.05 (0.97–1.14)	0.228	—	—
Treatment
Radical
BSC/surgery/RT	37/26/8	0.61 (0.48–0.78)	0.001	—	—
Palliative
Chemo/RT/BSC	59/27/47	1.22 (1.01–1.46)	0.039	1.30 (1.08–1.55)	0.004