Research Article
Simple and Objective Prediction of Survival in Patients with Lung Cancer: Staging the Host Systemic Inflammatory Response
Table 6
The relationship between parameters and survival in patients with mGPS = 2
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| | Parameter | Patients | Univariate | Multivariate | | HR (95% CI) | value | HR (95% CI) | value |
| | Age | | | | | | | | | <60/60–69/70–79/≥80 | 34/57/91/49 | 1.13 (0.98–1.30) | 0.084 |
— | — | | Sex | | | | | | | | | Male | 133 | 1 | 0.136 | — | — | | Female | 98 | 0.81 (0.61–1.07) | — | — | — | | Centre | | | | | | | | | Aberdeen | 43 | 1 | 0.002 | — | — | | Fife | 16 | 1.71 (0.95–3.06) | — | — | — | | Stobhill | 114 | 0.64 (0.45–0.92) | — | — | — | | Inverclyde | 45 | 0.88 (0.57–1.35) | — | — | — | | Deprivation (quintile) (most deprived = 1, least deprived = 5) | | | | | | | 1/2/3/4/5 | 111/21/70/20/9 | 1.05 (0.94–1.17) | 0.408 | — | — | | Smoking history (NS = never smoker, otherwise pack years) | | | | | | | NS/<20/20–60/>60 | 13/21/128/57 | 0.83 (0.69–1.00) | 0.062 | — | — | | Performance status | | | | | | | 0/1/2/3/4 | 5/51/88/66/21 | 1.51 (1.30–1.76) | <0.001 | 1.44 (1.21–1.71) | <0.001 | | Weight loss (% body weight) | | | | | | | 0/<5/5–10/>10 | 79/45/33/73 | 1.25 (1.11–1.40) | <0.001 | 1.13 (1.00–1.28) | 0.047 | | FEV1 (%) | | | | | | | >80/80–60/59–40/<40 | 130/33/47/17 | 0.88 (0.77–1.01) | 0.073 | — | — | | Local symptoms | | | | | | | No/Yes | 29/137 | 1.51 (0.98–2.33) | 0.063 | — | — | | Stage | | | | | | | NSCLC | | | | | | | I/II/IIIa/IIIb/IV | 7/5/12/36/79 | 1.32 (1.15–1.50) | <0.001 | — | — | | SCLC | | | | | | | Limited/extensive | 8/18 | 1.01 (0.91–1.12) | 0.826 | — | — | | Treatment | | | | | | | | Radical | | | | | | | BSC/surgery/RT | 18/2/4 | 0.52 (0.33–0.83) | 0.006 | — | — | | Palliative | | | | | | | Chemo/RT/BSC | 50/49/75 | 0.92 (0.78–1.10) | 0.364 | — | — |
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