Research Article

Malignant Pleural Mesothelioma Outcomes in the Era of Combined Platinum and Folate Antimetabolite Chemotherapy

Table 1

Baseline demographic data.

Malignant pleural mesothelioma ()245 patients
Age, median (range), y68 (21 to 88)
Gender, number (%)
 Men213 (86.9%)
 Women32 (13.1%)
Known asbestos, number (%)
 Yes123 (50.2%)
 No122 (49.8%)
Eastern Cooperative Oncology Group (ECOG) performance status, number (%)
 037 (15.1%)
 1117 (47.8%)
 251 (20.8%)
 319 (7.8%)
 42 (0.8%)
 Unknown19 (7.8%)
Initial staging, number (%)
 I84 (34.3%)
 II20 (8.2%)
 III69 (28.2%)
 IV63 (25.7%)
 Unknown9 (3.7%)
Histology, number (%)
 Epithelial154 (62.9%)
 Sarcomatoid34 (13.9%)
 Mixed27 (11%)
 Unknown30 (12.2%)
Laterality, number (%)
 Left97 (39.6%)
 Right138 (56.3%)
 Bilateral5 (2%)
 Unknown5 (2%)
Presenting symptoms and signs, number (%)
 Dyspnea186 (75.9%)
 Pleural effusion179 (73.1%)
 Chest pain118 (48.2%)
 Weight loss (≥5%)89 (36.3%)
 Cough71 (29%)
 Dysphagia7 (2.9%)
 Pericardial effusion5 (2%)