Cell-Type-Specific Effects of Silibinin on Vitamin D-Induced Differentiation of Acute Myeloid Leukemia Cells Are Associated with Differential Modulation of RXRα Levels
Figure 4
Effects of 1,25D, carnosic acid and silibinin, alone and in combination, on VDR and RXRα protein expression in HL60 and U937 cells. Cells were treated for 48 h (1 × 105 cells/mL; (a), (c)) or 96 h (4 × 104 cells/mL; (b), (d)) with 0.1% ethanol (control) or the indicated test agents. Protein expression was then determined by Western blotting. Calreticulin (CRN) was used as the protein loading control. Representative blots of at least 3 independent experiments are shown.
