Review Article

Regulation of Leukemic Cell Differentiation through the Vitamin D Receptor at the Levels of Intracellular Signal Transduction, Gene Transcription, and Protein Trafficking and Stability

Figure 4

Expression of monocytic differentiation markers in AML cell lines exposed to either 1,25(OH)2D or to PRI-1907. HL60, U-937, NB-4, MV4-11, and MOLM-13 cells were exposed either to 1,25(OH)2D (a, b) or to PRI-1907 (c, d) for 96 h, and then the expression of CD11b and CD14 was tested in flow cytometry. The graphs show mean percentages (±SEM) of cells expressing cell differentiation markers. Based on [40].
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(a)
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(b)
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