Isochromosome 17q in Chronic Lymphocytic Leukemia

Table 1

Gender, age, and cytogenetic results of the 18 studied CLL cases which showed deletion of TP53 gene.

Case number	Gender	Age [y]	DNA extracted from	Banding cytogenetics
1	F	74	bm	46,XX,i(17)(q10)1]/; 46,XX,+12,i(17)(q10),-219]/; 46,XX,t(3;?)(q2?9;?)4],-74],+124],i(17)(q10)4]cp4]/; 46,XX4]
2	M	83	bm	47,XY,-11,+12,+marcp3]/; 47,XY,del(5)(p1?3),-11,+12,-17,+mar1,+mar2cp6]/; 46,XY9]
3	M	72	bm	46,XY
4	F	71	b	46,XX
5	F	50	b	n.a.
6	M	65	bm	46,XY,?t(3;?)(p21;?),der(17)t(17;?),-18,+marcp7]/; 46,XY9]
7	F	66	b	n.a.
8	M	73	bm	46~47,XY,del(11)(q22q2?3),der(17)t(17;?)(p11.2;?)cp5]/; 45~46,XY,del(11)(q22q2?3),del(17)(p11.2)cp4]/; 43~46,XY,del(11)(q22q2?3)cp2]/; 46,XY7]
9	F	74	B	46,XX
10	F	90	b	n.a.
86	M	74	n.a.	45~46,XY,i(17)(q10)cp4]/; 45,X,-Y2]/; 46,XY14]
87	F	76	n.a.	46,XX,?t(6;19)(p22;p13),del(17)(p?11.2)1]; 46,XX16]
88	M	65	n.a.	46,XY,t(10;13)(q2?2;q1?3)10]; 46,XY,i(18)(q10)1]; 45,XY,?del(6)(?q21),-171]; 46,XY,-17,+mar1]; 44,XY,-11,-171]; 46,XY,-4,-21,+2mar1]; 46,XY5]
89	F	68	n.a.	n.a.
90	F	63	n.a.	n.a.
91	F	79	n.a.	n.a.
92	M	61	n.a.	n.a.
93	F	75	n.a.	n.a.

b = cell pellet in Carnoy’s fixative from blood; bm = cell pellet in Carnoy’s fixative from bone marrow; F = female; M = male; n.a. = not available; B = native peripheral blood.