Isochromosome 17q in Chronic Lymphocytic Leukemia

Table 4

All 18 CLL cases which revealed TP53 deletion are listed showing the additionally detected chromosomal aberrations and their clinical impact (1).

Case number	Additional aberrations not listing #17 aberrations [%]	Prognosis
1	t(3;?)(q2?9;?)22]	n.a.
	-722]	Adverse
	+1278]	Intermediate
	del(14)(q32q32)94]	Good
	-2150]	n.a.
2	del(5)(p1?3)33]	n.a.
	del(11)(q22.3q22.3)30]	Adverse
	+1270]	Intermediate
	del(13)(q14.3q14.3)30]	Good
	rea(14)(q32.33)28] -> ?+14	Adverse
3	del(13)(q14.3q14.3)20]	Good
4	None detected	Intermediate
5	del(13)(q14.2q14.2)52]	Good
	del(13)(q14.2q14.2)x238]
	del(13)(q14.3q14.3)34]
6	t(3;?)(p21;?)44]	n.a.
	-18,+mar44]	n.a.
7	del(13)(q14.3q14.3)90.5]	Good
8	amp(8)(q24.21q24.21)21]	Adverse
	del(11)(q22.3q22.3)11]	Adverse
9	None detected	Intermediate
10	del(13)(q14.3q14.3)x298.5]	Good
86	-Y	n.a.
87	?t(6;19)(p22;p13),del(17)(p?11.2)	Adverse
88	t(10;13)(q2?2;q1?3)	Advesrse
	i(18)(q10)	n.a.
	?del(6)(?q21),-17	n.a.
	-17,+mar	n.a.
	-11,-17	n.a.
	-4,-21,+2mar	n.a.
	del(13)(q14.3q14.3)57]	Good
	del(14)(q32q32)75]	Good
89	del(13)(q14.2q14.2)50]	Good
	del(13)(q14.2q14.2)x27]
90	del(14)(q32q32)36]	Good
91	None detected	Intermediate
92	None detected	Intermediate
93	None detected	Intermediate

n.a. = not available.