Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells

<div>Metformin induces changes in enzymes controlling energy metabolism. Western blots of PKC<i>δ</i> and PKC<i>ε</i> in CEM, 10E<sub>1</sub>-CEM, and R5-CEM cells exposed to 10 mM metformin for the times indicated. Representative results of three independent assays performed are shown.</div>

Leukemia Research and Treatment

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Figure 8

Figure 8: Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells 