Research Article

Non-Hodgkin Lymphoma in Children with Primary Immunodeficiencies: Clinical Manifestations, Diagnosis, and Management, Belarusian Experience

Table 1

Characteristics of patients with NHLa.

CharacteristicPatients with PIDb, (%)Immunocompetent patients, (%)

Sex
 M10 (62.5)220 (79.2)
 F6 (37.5)57 (20.8)
Age
 0–46 (37.5)52 (18.8)
 5–95 (31.25)85 (30.7)
 10–142 (12.5)86 (31.0)
 ≥153 (18.75)54 (19.5)
Stage
 I + II1 (6.25)77 (27.8)
 III + IV15 (93.75)200 (72.2)
Morphology
 Burkitt2 (12.5)135 (48.7)
 T-lymphoblastic3 (18.75)52 (18.8)
 B-lymphoblastic019 (6.9)
 DLBCLc6 (37.5)16 (5.8)
 PMLBCLd014 (5.1)
 ALCLe systemic2 (12.5)33 (11.9)
 ALCL cutaneous1 (6.25)0
 PTCLf2 (12.5)2 (0.7)
 B-NHL, unspecified06 (2.2)
Immunological lineage
 B8 (50.0)190 (68.6)
 T8 (50.0)87 (31.4)

Non-Hodgkin lymphoma, bprimary immune deficiency disease, cdiffuse large B-cell lymphoma, dprimary mediastinal large B-cell lymphoma, eanaplastic large cell lymphoma, and fperipheral T-cell lymphoma.