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Marcel Gielen, Abdelaziz El Khloufi, Monique Biesemans, Abdeslam Bouhdid, Dick de Vos, Bernard Mahieu, Rudolph Willem, "Synthesis, Characterization and High In Vitro Antitumour Activity of Novel Triphenyltin Carboxylates", Metal-Based Drugs, vol. 1, Article ID 194963, 5 pages, 1994. https://doi.org/10.1155/MBD.1994.305
Synthesis, Characterization and High In Vitro Antitumour Activity of Novel Triphenyltin Carboxylates
Abstract
The synthesis and spectral characterization of six novel triphenyltin compounds are described. The in vitro antitumour activity of three of these compounds against two human tumour cell lines, MCF-7, a mammary tumour, and WiDr, a colon carcinoma, was determined. All three compounds are more active than cis-platin, etoposide and doxorubicin against both tumour cell lines. They are as active as mitomycin C against WiDr, but less active against MCF-7.
Copyright
Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
