Open Access
M. Coluccia, A. Boccarelli, C. Cermelli, M. Portolani, G. Natile, "Platinum(II)-Acyclovir Complexes: Synthesis, Antiviral and Antitumour Activity", Metal-Based Drugs, vol. 2, Article ID 835735, 8 pages, 1995. https://doi.org/10.1155/MBD.1995.249
Platinum(II)-Acyclovir Complexes: Synthesis, Antiviral and Antitumour Activity
Abstract
A platinum(II) complex with the antiviral drug acyclovir was synthesized and its
antiviral and anticancer properties were investigated in comparison to those of acyclovir and
cisplatin. The platinum-acyclovir complex maintained the antiviral activity of the parent
drug acyclovir, though showing a minor efficacy on a molar basis (
Copyright
Copyright © 1995 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.