Table of Contents
Metal-Based Drugs
Volume 3 (1996), Issue 5, Pages 233-240

Complexes With Biologically Active Ligands. Part 71 Synthesis and Fungitoxic Activity of Metal Complexes Containing 1,3,5-tris-(8-Hydroxyquinolino)- Trichlorocyclo-Triphosphazatriene

1Research Center for Macromolecular Materials and Membranes, Splaiul Independentei 206, Bucharest 79611, Romania
2Polytechnic University of Bucharest, Department of Inorganic Chemistry, Polizu Str. 1, Bucharest 79611, Romania
3University of Bucharest, Department of Inorganic Chemistry, Str. Dumbrava Rosie 23, Bucharest, Romania
4Università degli Studi, Dipartimento di Chimica, Laboratorio di Chimica Inorganica e Bioinorganica, Via Gino Capponi 7, Florence I-50121, Italy

Received 16 September 1996; Accepted 17 September 1996

Copyright © 1996 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Complexes containing 1,3,5-tris-(8-hydroxyquinolino)-trichlorocyclotriphosphazatriene, a new cyclophosphazene ligand, and Co(II), Cu(II) and Ni(II) were prepared. The new complexes, having the general formula [MLCl2], [ML2]Cl2, (M=Cu, Co, Ni); [NiLAc], [NiL2Ac]Ac and [ML3]X3 (M=Ni, Co, X=Cl, Ac) were characterised by elemental analysis, electronic-, IR spectroscopy, and electrical conductivity measurements. Some of them inhibited the growth of several fungi species (Aspergillus and Candida spp.)