Table of Contents
Metal-Based Drugs
Volume 5, Issue 6, Pages 333-335

Distribution of Copper in Rats Submitted to Treatment With Copper Aspirinate

1Institute of Precious Metals, Kunming 650221, China
2Kunming Medical College, Kunming 650031, China

Received 22 June 1998; Accepted 18 November 1998

Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The distribution of copper in Sprague – Dawley rats following a three month oral administration of 0,10 or 50mg/kg copper aspirinate has been investigated. Metal content was determined by ICP – AES in blood, brain, kidney, liver, lung, spleen, and dejection. The results show that treatment with copper aspirinate did not cause accumulation of copper in rats and excess ingested copper was excreted through feces.