A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)-
hydrazide (HL1)
and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL2)
have been synthesized and
characterized by their IR, H1
NMR, C13
NMR and microanalytical date. The biological effect induced due to the coupling of ferrocene molecule with the aroylhydrazines e.g., pyrazinoylhydrazine and nicotinoylhydrazine has been studied against bacterial species such as Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus and Klebsiella pneumonae.