Metal-Based Drugs

Metal-Based Drugs / 1999 / Article

Open Access

Volume 6 |Article ID 852089 | https://doi.org/10.1155/MBD.1999.81

Anupa Murugkar, Subhash Padhye, Deepti Deobagkar, "Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities", Metal-Based Drugs, vol. 6, Article ID 852089, 5 pages, 1999. https://doi.org/10.1155/MBD.1999.81

Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities

Received19 Jan 1999
Accepted05 Feb 1999

Abstract

Iron(II) and iron(III) complexes of 3,5-di-tert-butyl-o-benzoquinonemonooxime were synthesized and characterized by spectroscopic and electrochemical studies. Their ability to cleave DNA has been investigated under aerobic conditions at room temperature and in the presence and absence of H2O2 . The plasmid DNA pBR322 was effectively cleaved by these complexes in a concentration dependant manner.

Copyright © 1999 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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