Table of Contents
Metal-Based Drugs
Volume 8, Issue 5, Pages 293-302

Efficacy of Organophosphorus Derivatives Containing Chalcones/Chalcone Semicarbazones Against Fungal Pathogens of Sugarcane

1Department of Chemistry, DDU Gorakhpur University, Gorakhpur 273009, India
2Sugar Cane Research station, Kunraghat, Gorakhpur 273008, India

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Ten newly synthesized organophosphorus derivatives containing substituted chalcones and substituted chalcone semicarbazones were tested for their antifungal efficacy against Colletotrichum falcatum, Fusarium oxysporum, Curvularia pallescens (all sugarcane pathogens). The O,O-diethylphosphate derivatives containing 2-chlorochalcone and 2-chlorochalcone semicarbazone exhibited 70-85% mycelial inhibition against all the test fungi at 1000 ppm. The screening results were correlated with structural features of the tested compounds.