Table of Contents
Metal-Based Drugs
Volume 8, Issue 5, Pages 257-262

Synthesis and Biological Activity of Organothiophosphoryl Polyoxotungstates

Department of Chemistry, Northeast Normal University, Changchun 130024, China

Received 29 January 2002; Accepted 19 February 2002

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Organothiophosphoryl polyoxotungstates R2XW11O39n , R2P2W17O616 , R2PW9O345 , (X = P, Si, Ge, B or Ga; R = PhP(S), C6H11P(S)) have been prepared from lacunary polyoxoanions and PhP(S)Cl2 or C6H11P(S)Cl2. The products were characterized by elemental analysis, IR, P31 and W183 NMR spectroscopy. According to spectroscopic observations, the hybrid anions consist of a lacunary anion framework on which are grafted two equivalent C6H5P(S) or C6H11P(S) groups through P-O-W bridges. Some of the title compounds showed the antigerm activity.