Photodynamic Therapy and the Development of Metal-Based Photosensitisers

Table 2

Summary of a collection of different photosensitiser types and their absorption data.

CLASS OF PHOTOSENSITISER	LONGEST	EXTINCTION	DRUGS IN	DRUGS
	WAVELENGTH	COEFFICIENT/	CLINICAL TRIAL	APPROVED FOR
	ABSORPTION/nm	M^−1cm^−1	(Phase I–III)	PDT (PRECLINICAL
				AND CLINICAL)
Porphyrins	620–640	3,500	—	Photofrin
				Levulan
				Metvix
(Expanded Porphyrins)				ATMPn
Porphycenes Texaphyrins	610–650 730–770	50,000\ \ \ \ \ \ 40,000	Lu-Tex
			Optrin
			Antrin
			Xcytrin
			Benzvix
			Hexvix
Chlorins	650–690	40,000	Foscan	Visudyne
			Puryltin
Bacteriochlorins	730–800	150,000	—	—
Phthalocyanines	680–780	200,000	CGP55847	—
			PC4
			Photosense
Naphthalocyanines	740–780	250,000	—	—