Photodynamic Therapy and the Development of Metal-Based Photosensitisers

Table 3

Summary of a range of photosensitisers and their clinical applications.

TRADE NAME	MARKETING COMPANY	PRE-/CLINICAL APPLICATION	COUNTRIES APPROVED IN
Photofrin	QLT Phototherapeutics	Oesophageal, lung, bladder and cervical dysplasia	Canada (1993),
			The Netherlands (1994),
			Japan (1994),
			USA (1995),
			France (1996),
			Germany (1997),
			Finland (1999),
			UK (1999),
			Sweden (2000),
			Italy (2000),
			Ireland (2000),
			Poland (2000)
Levulan	DUSA Pharmaceuticals	Actinic keratosis	USA (1999),
		Actinic keratosis and	Sweden (2001),
		basal-cell carcinoma	Europe (2001)
Metvix	Photocure ASA	Actinic keratosis and	Sweden (2001),
		basal-cellcarcinoma	Europe (2001)
Visudyne	QLT Phototherapeutics	Wet-AMD	Europe (2001),
			USA (2000),
			Canada (2000),
		Subfoveal choroidal neovascularisation	Europe (2001),
			USA(2001),
			Canada (2001)
ATMPn	GlaxoWellcome and Cytopharm	Psorasis and non-melanoma skin cancer	Germany (1997)
Purlytin	Miravant Medical Technologies	Psorasis and restenosis	USA (1998)
Foscan	BioLitec Pharmaceuticals	Head and neck cancers	Europe (2001)