Synthesis, Structure, Electrochemistry, and Spectral Characterization of Bis-Isatin Thiocarbohydrazone Metal Complexes and Their Antitumor Activity Against Ehrlich Ascites Carcinoma in Swiss Albino Mice

Table 5

Comparative effects of treatments versus cisplatin on reduction of body weights in tumor-induced mice.

Group	Dose (mg/kg) i.p.	% Decrease in weight as compared to respective control (Mean ± SE)
		Day 12 (Mean ± SE)	Day 15 (Mean ± SE)
Cisplatin	3.5	42.22±11.32	93.10±12.31
[Cu(L)Cl]⋅2H2O	50	10.49±9.31	76.19±10.31
[Cu(L)OAc]⋅2H2O	50	11.14±6.43	66.79±12.70
Ligand	50	3.56±9.28	59.48±5.68